CRISPR Screen Dataset
Seneviratne AK (2019) - 1-PMID30930145
Title: The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Acute Myeloid Leukemia Cell Line [BTO:0001883]
- Cell Line : OCI-AML-2 [BTO:0004619, CELLOSAURUS:CVCL_1619]
- Phenotype : Cell Proliferation
- Library : TKO (Toronto Knockout) v1 [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : MaGeCK | Number of Hits: 147 | Full Dataset Size: 1,049
- Experimental Setup : Timecourse | Duration: 17 Days
- Significance : Authors have indicated that results with Score.3 (FDR) < 0.05 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 0.99956
> 0.00000000439