Screen Summary
Shalem O (2014) - 3-PMID24336571
Title: Genome-scale CRISPR-Cas9 knockout screening in human cells.
Screen Details:
- Screen Type : Positive Selection | Format: Pool
- Cell Line : A-375 cell | Type: Melanoma Cell Line
- Throughput : High Throughput
- Enzyme : CAS9
- Phenotype : Resistance To Chemicals
- Experimental Setup : Drug Exposure | Duration: 14 Days | Condition Name: Vemurafenib (2 µM) | MOI: = 0.3
- Library : GECKO | Type: CRISPRn | Methodology: Knockout
- Analysis Method : RIGER | Number of Hits: 100 | Full Dataset Size: 18,080
- Significance : Authors have indicated that ALL results are to be considered significant.
Score Distribution
< 0.04346
> 0.0007519