CRISPR Screen Dataset

Name: CRISPR SCREEN: Shalem O (2014) - 3-PMID24336571 (Genome-scale CRISPR-Cas9 knockout screening in human cells.)
Creator: BioGRID Project

Shalem O (2014) - 3-PMID24336571

H. sapiens

Title: Genome-scale CRISPR-Cas9 knockout screening in human cells.

Screen Rationale : Increased drug resistance
Cell Type : Melanoma Cell Line [BTO:0000849]
Cell Line : A-375 [BTO:0002806]
Phenotype : Response To Chemicals
Condition : Vemurafenib (2 µM) [ChEBI]
Library : GECKO | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
Analysis Method : RIGER | Number of Hits: 100 | Full Dataset Size: 18,080
Experimental Setup : Drug Exposure | Duration: 14 Days | MOI: = 0.3
Significance : Authors have indicated that ALL results are to be considered significant.

< 0.04346

> 0.0007519