CRISPR Screen Dataset

Fei T (2017) - 1-PMID28611215

Title: Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

Screen Details:

Notes:
  • Genes with a significant negative MAGeCK score are cell-essential genes in the LNCaP cell line, their KO results in decreased proliferation
  • Genes with a significant positive MAGeCK score are growth restrictive genes in the LNCaP cell line, their KO results in increased proliferation

Score Distribution

< 0.99998
> 0.00000167

CRISPR Screen Results (1991 hits)