CRISPR Screen Dataset
Wang T (2017) - 19-PMID28162770
Title: Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.
Screen Details:
- Screen Rationale : Cell-essential genes (mouse pro-B cells)
- Screen Type : Negative Selection | Format: Pool
- Cell Line : BA/F3 cell | Type: Pre-B-Lymphocyte Cell Line
- Throughput : High Throughput
- Enzyme : CAS9
- Phenotype : Viability
- Experimental Setup : Timecourse | Duration: 14 Doublings | Condition Name: Murine Interleukin 3 (1 ng/mL)
- Library : Mouse Two Plasmid Activity-Optimized CRISPR Knockout Library | Type: CRISPRn | Methodology: Knockout
- Analysis Method : Log2 Fold Change (L2FC) | Number of Hits: 3,761 | Full Dataset Size: 18,987
- Significance : Authors have indicated that results with Score.1 (Log2) < -1 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 2.395
> -7.341