Screen Summary

Wang T (2017) - 18-PMID28162770

M. musculus

Title: Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

Screen Type : Negative Selection | Format: Pool
Cell Line : BA/F3 cell | Type: Pre-B-Lymphocyte Cell Line
Throughput : High Throughput
Enzyme : CAS9
Phenotype : Viability
Experimental Setup : Timecourse | Duration: 14 Doublings | Condition Name: Murine Interleukin 3 (1 ng/mL)
Library : Mouse Two Plasmid Activity-Optimized CRISPR Knockout Library | Type: CRISPRn | Methodology: Knockout
Analysis Method : Log2 Fold Change (L2FC) | Number of Hits: 3,296 | Full Dataset Size: 18,987
Significance : Authors have indicated that results with Score.1 (Log2) < -1 are to be considered significant. These results are indicated by 'Yes' in the HIT column of the table below.

< 1.966

> -7.324