CRISPR Screen Dataset
Ma Y (2017) - 1-PMID28494239
Title: CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Screen Details:
- Screen Rationale : Cell-essential genes in an Epstein-Barr Virus (EBV) latency I state
- Cell Type : Epstein-Barr Virus (EBV)+ Burkitt Lymphoma Cell Line (EBV Latency I State)
- Cell Line : P3HR-1 [EFO:0002312, CELLOSAURUS:CVCL_2676, DEPMAP:ACH-000707]
- Phenotype : Cell Proliferation
- Library : Avana | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : STARS | Number of Hits: 57 | Full Dataset Size: 18,675
- Experimental Setup : Timecourse | Duration: 21 Days | MOI: = 0.3
- Significance : Authors have indicated that ALL results are to be considered significant.
Notes:
- authors used a cut-off of q-value < 0.05 to determine hits
Score Distribution
< 12.82744736
> 4.149119577