CRISPR Screen Dataset
Ma Y (2017) - 2-PMID28494239
Title: CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors.
Screen Details:
- Screen Rationale : Cell-essential genes in an Epstein-Barr Virus (EBV) latency III state
- Cell Type : Epstein-Barr Virus (EBV)+ Lymphoblastoid Cell Line (EBV Latency III State)
- Cell Line : GM12878 [EFO:0002784, CELLOSAURUS:CVCL_7526]
- Phenotype : Cell Proliferation
- Library : Avana | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : STARS | Number of Hits: 87 | Full Dataset Size: 18,675
- Experimental Setup : Timecourse | Duration: 21 Days | MOI: = 0.3
- Significance : Authors have indicated that ALL results are to be considered significant.
Notes:
- authors used a cut-off of q-value < 0.05 to determine hits
Score Distribution
< 10.46814522
> 4.209345731