CRISPR Screen Dataset
Toledo CM (2015) - 4-PMID26673326
Title: Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Neural Stem Cell Line [BTO:0002891]
- Cell Line : NSC-U5
- Phenotype : Cell Proliferation
- Library : GECKO | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : BAGEL | Number of Hits: 1,933 | Full Dataset Size: 18,076
- Experimental Setup : Timecourse | Duration: 21 Days | MOI: < 1
- Significance : Authors have indicated that results with Score.1 (Bayes Factor) > 3.0 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- This data set contains 3 ambiguous gene names and 75 unknown genes that were not loaded into ORCS.
Score Distribution
< 67.356
> -37.578