CRISPR Screen Dataset

Pan D (2018) - 4-PMID29301958

Title: A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.

Screen Details:

  • The authors screened for gene knockouts in a melanoma cell line that conferred increased resistance to killing by cytotoxic OT-I T cells, which have a high TCR affinity for an endogenous melanoma antigen

Score Distribution

< 5.36
> 0.84

CRISPR Screen Results (22 hits)