Screen Summary

Pan D (2018) - 2-PMID29301958

Title: A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.

Screen Details:

Notes:
  • The authors screened for gene knockouts in a melanoma cell line that conferred increased resistance to killing by cytotoxic Pmel-1 T cells, which have a relatively low TCR affinity for an endogenous melanoma antigen

Score Distribution

< 9.69
> 0.71

CRISPR Screen Results (73 hits)