Screen Summary

Breslow DK (2018) - 1-PMID29459677

Title: A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

Screen Details:

Notes:
  • The authors screened for genes affecting ciliary Hh signaling using a a reporter that converts Hh signaling into antibiotic resistance. Genes with a positive CasTLE effect increase Hh pathway signaling while genes with a negative CasTLE effect decrease Hh pathway signaling

Score Distribution

< 237
> 0

CRISPR Screen Results (472 hits)