Screen Summary

Konermann S (2015) - 2-PMID25494202

H. sapiens

Title: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Screen Type : Positive Selection | Format: Pool
Cell Line : A-375 cell | Type: Melanoma Cell Line
Throughput : High Throughput
Enzyme : SAM (NLS-dCas9-VP64/MS2-p65-HSF1)
Phenotype : Resistance To Chemicals
Experimental Setup : Drug Exposure | Duration: 21 Days | Condition Name: PLX-4720 (2 µM) | MOI: < 0.2
Library : SAM v1 (Puromycin) | Type: CRISPRa | Methodology: Activation
Analysis Method : RIGER | Number of Hits: 100 | Full Dataset Size: 23,430
Significance : Authors have indicated that ALL results are to be considered significant.

< 1.8175

> 1.5831