CRISPR Screen Dataset

Baxter JS (2023) - 1-PMID37866880

Title: Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.

Screen Details:

Notes:
  • Authors screened for genes that were synthetic lethal with an FBXW7 mutant (FBXW7-17) upon KO
  • FBXW7-17 contained a 2093 bp deletion within FBXW7 (between genomic coordinates chr4:152328220 and 152330312)

Score Distribution

< 8.643160152
> -14.71759797

CRISPR Screen Results (462 hits)