CRISPR Screen Dataset
Morgens DW (2016) - 1-PMID27159373
Title: Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.
Screen Details:
- Screen Rationale : Cell-essential genes and growth restrictive genes
- Cell Type : Chronic Myeloid Leukemia Cell Line [BTO:0002580]
- Cell Line : K-562 [BTO:0000664, CELLOSAURUS:CVCL_0004]
- Phenotype : Cell Proliferation
- Library : CRISPRn (Bassik, 2016) | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : CasTLE | Number of Hits: 1,878 | Full Dataset Size: 18,509
- Experimental Setup : Timecourse | Duration: 14 Days
- Significance : Authors have indicated that results with Score.2 (p-Value) <= 0.05 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- Negative CasTLE scores correspond to decreased growth, positive CasTLE scores indicate increased growth
Score Distribution
< 95.9
> -222