CRISPR Screen Dataset
Mei H (2021) - 1-PMID34686207
Title: Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist.
Screen Details:
- Screen Rationale : Cell-essential genes and growth restrictive genes
- Cell Type : HeLa [BTO:0000567, CELLOSAURUS:CVCL_0030]
- Cell Line : H1HeLa [CLO:0003586, CELLOSAURUS:CVCL_3334]
- Phenotype : Cell Proliferation
- Library : CRISPRn (Liu, 2021) | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : MaGeCK | Number of Hits: 60 | Full Dataset Size: 18,754
- Experimental Setup : Timecourse | Duration: 10 Days | MOI: = 0.3
- Significance : Authors have indicated that results with Score.2 (FDR) < 0.001 OR Score.4 (FDR) < 0.001 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- Genes with a significant negative FDR represent genes whose KO results in decreased cellular proliferation, genes with a significant positive FDP represent genes whose KO results in increased cellular proliferation
Score Distribution
< 1
> 0.000000000511