CRISPR Screen Dataset
Morgens DW (2017) - 1-PMID28474669
Title: Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Lymphoma Cell Line [BTO:0000104]
- Cell Line : U-937 [BTO:0001412, CELLOSAURUS:CVCL_0007]
- Phenotype : Cell Proliferation
- Library : Bassik Human CRISPR Knockout Library [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : CasTLE | Number of Hits: 2,264 | Full Dataset Size: 20,533
- Experimental Setup : Timecourse | Duration: 14 Days
- Significance : Authors used a complex method to determine significant results. Please refer to the source publication for more details. Significant results are indicated by ' ' in the HIT column of the table below.
Notes:
- authors used a cut-off of FDR<= 10% to determine significance
Score Distribution
< 549
> 0