Screen Summary
Wang T (2015) - 2-PMID26472758
Title: Identification and characterization of essential genes in the human genome.
Screen Details:
- Screen Type : Negative Selection | Format: Pool
- Cell Line : K-562 cell | Type: Chronic Myeloid Leukemia Cell Line
- Throughput : High Throughput
- Enzyme : CAS9
- Phenotype : Viability
- Experimental Setup : Timecourse | Duration: 14 Doublings
- Library : Activity-optimized genome-wide library | Type: CRISPRn | Methodology: Knockout
- Analysis Method : Kolmogorov-Smirnov | Number of Hits: 1,660 | Full Dataset Size: 18,166
- Significance : Authors have indicated that results with Score.1 (CRISPR Score (CS)) < -0.1 AND Score.2 (p-Value) < 0.05 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- Genes with a CRISPR Score (CS) < -0.1 and corrected p-value < 0.05 are considered significant.
Score Distribution
< 1.674
> -5.784