Screen Summary

Steinhart Z (2017) - 1-PMID27869803

Title: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Screen Details:

  • Genes with a Bayes Factor (BF) above the threshold of 3.00 at an FDR of 5% (FDR < 0.05) were identified as fitness genes (hits) for this cell line in this CRISPR screen.

Score Distribution

< 104.16
> -634.6

CRISPR Screen Results (2174 hits)