CRISPR Screen Dataset
Martin TD (2017) - 3-PMID28700943
Title: A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Cecum Cancer Cell Line [BTO:0004746]
- Cell Line : LS513 [CLO:0007407, CELLOSAURUS:CVCL_1386]
- Phenotype : Cell Proliferation
- Library : CRISPRn (Martin, 2017) | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : EdgeR | Number of Hits: 62 | Full Dataset Size: 17,875
- Experimental Setup : Timecourse | Duration: 10 Doublings | MOI: = 0.2
- Significance : Authors have indicated that results with Score.1 (FDR) < 0.05 AND Score.2 (Log2) < -1.0 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 1
> 0.00099