BioGRID ORCS News

7,592 budding yeast protein interactions from systematic mass spectrometric analysis of protein complexes were added to BioGRID from the paper:

Proteome survey reveals modularity of the yeast cell machinery
Gavin AC, Aloy P, Grandi P, Krause R, Boesche M, Marzioch M, Rau C, Jensen LJ, Bastuck S, Dumpelfeld B, Edelmann A, Heurtier MA, Hoffman V, Hoefert C, Klein K, Hudak M, Michon AM, Schelder M, Schirle M, Remor M, Rudi T, Hooper S, Bauer A, Bouwmeester T, Casari G, Drewes G, Neubauer G, Rick JM, Kuster B, Bork P, Russell RB, Superti-Furga G.
Nature Mar (2006); 440:631-6

Note: Interactions corresponding to all 491 complexes defined in Gavin et al were abstracted from the raw interaction dataset. Purification and complex information is available at the IntAct database: http://www.ebi.ac.uk/intact/.