390 New Interactions from the Gingras and Aebersold Groups

The BioGRID has added 390 new physical interactions as reported in Gingras et al: “A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity” (Mol Cell Proteomics 2005 Nov 4; PMID: 16085932), Goudreault et al: “A PP2A phosphatase high-density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein” (Mol Cell Proteomics 2008 Sep 8 issue; Epub ahead of print; PMID: 18782753) and Chen et al: “PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4 (J Biol Chem 2283:29273-84; Epub 2008 Aug 20; PMID: 18715871). These datasets are available via our downloads page ( A special thanks to all the contributing the authors from these papers Aebersold R, Caballero M, Chaudhry S, Chen GI, D’Ambrosio LM, Fields S, Gingras AC, Goudreault M, Hafen E, Hazbun TR, Jorgensen C, Kean, MJ, Larsen BG, Mullin M, Nesvizhskii AI, Qu H, Raught B, Sanchez A, Sicheri F, Sonenberg N, Tisayakorn S and Zarske M. If you have an interaction dataset you’d like to deposit directly into the BioGRID, please contact us at

October 1st, 2008 - 12:45 PM