New Dataset of 56,473 Human Affinity Capture-MS Interactions

The BioGRID has loaded a new comprehensive Affinity Capture-MS dataset of 56,473 high confidence protein interactions in Human as reported by Huttlin EL et al in the publication: "Architecture of the human interactome defines protein communities and disease networks." (Nature 2017) [Nature][BioGRID][Pubmed]. The dataset and associated modified CompPASS scores are available immediately online via all standard BioGRID searches and supported download formats.

A special thanks to the contributors Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, and Harper JW

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at

June 6th, 2017 - 09:03 PM