New Dataset of 326,790 Saccharomyces cerevisiae Genetic Interactions

The BioGRID has loaded a new comprehensive SGA dataset of 326,790 high confidence genetic interactions in the budding yeast Saccharomyces cerevisae as reported by Costanzo et al in the publication: "A global genetic interaction network maps a wiring diagram of cellular function." (Science 2016) [Science][BioGRID][Pubmed]. The dataset and associated quantitative scores are available immediately online via all standard BioGRID searches and supported download formats.

A special thanks to the contributors Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, Lin ZY, Kuzmin E, Nelson J, Piotrowski JS, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat CF, Li SC, Li Z, Usaj MM, Okada H, Pascoe N, San Luis BJ, Sharifpoor S, Shuteriqi E, Simpkins SW, Snider J, Suresh HG, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya OG, Stagljar I, Xia T, Ohya Y, Gingras AC, Raught B, Boutros M, Steinmetz LM, Moore CL, Rosebrock AP, Caudy AA, Myers CL, Andrews B and Boone C.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at

December 7th, 2016 - 06:03 AM