CRISPR Screen Dataset
Niu Y (2021) - 1-PMID33813748
Title: Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.
Screen Details:
- Screen Rationale : Hypoxia-responding essential genes
- Cell Type : Hepatoma Cell Line [BTO:0000578]
- Cell Line : Hep-G2 [BTO:0000599, CELLOSAURUS:CVCL_0027]
- Phenotype : Response To Oxygen Concentration
- Condition : Low oxygen (1.0 %)
- Library : GECKO v2 [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : MaGeCK | Number of Hits: 3,103 | Full Dataset Size: 19,050
- Experimental Setup : Other | Duration: 3 Days
- Significance : Authors have indicated that ALL results are to be considered significant.
Score Distribution
< 0.33193
> 0.0000017416