CRISPR Screen Dataset
Lawson KA (2020) - 3-PMID32968282
Title: Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Breast Adenocarcinoma Cell Line [BTO:0001912]
- Cell Line : 4T1 [BTO:0004311, CELLOSAURUS:CVCL_0125]
- Phenotype : Cell Proliferation
- Library : mTKO (mouseTKO) | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : BAGEL | Number of Hits: 1,912 | Full Dataset Size: 19,466
- Experimental Setup : Timecourse | Duration: 14 Days | MOI: ~ 0.5
- Significance : Authors have indicated that results with Score.1 (Bayes Factor) > 5.0 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 192.045
> -3305.85