CRISPR Screen Dataset
Marceau CD (2016) - 1-PMID27383987
Title: Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens.
Screen Details:
- Screen Rationale : Increased resistance to virus
- Cell Type : Huh-7 Cell [BTO:0001950]
- Cell Line : Huh-7.5.1 [BTO:0005463, CELLOSAURUS:CVCL_E049]
- Phenotype : Response To Virus
- Condition : Virus: Dengue virus 2 Thailand/16681/84 (1 MOI) [NCBI Taxid 31634]
- Library : GECKO v2 [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : RIGER | Number of Hits: 30 | Full Dataset Size: 21,703
- Experimental Setup : Virus Exposure | Duration: 16 Days | MOI: = 0.3
- Significance : Authors have indicated that results with Score.1 (RIGER score) > 1.024 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- The authors focused downstream analysis on the 30 most enriched genes from the screen
Score Distribution
< 4.407860268
> -0.135662602