CRISPR Screen Dataset
Zhang R (2016) - 1-PMID27383988
Title: A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
Screen Details:
- Screen Rationale : Increased resistance to virus
- Cell Type : Embryonic Kidney Cell Line [BTO:0002733]
- Cell Line : HEK293T [BTO:0002181, CELLOSAURUS:CVCL_0063]
- Phenotype : Response To Virus
- Condition : Virus: West Nile virus (1 MOI) [NCBI Taxid 11077]
- Library : GECKO v2 [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : MaGeCK | Number of Hits: 12 | Full Dataset Size: 18,981
- Experimental Setup : Virus Exposure | Duration: 2 Weeks | MOI: = 0.3
- Significance : Authors have indicated that results with Score.1 (FDR) < 0.1 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 1
> 0.002475