CRISPR Screen Dataset
Zhang R (2018) - 1-PMID29769725
Title: Mxra8 is a receptor for multiple arthritogenic alphaviruses.
Screen Details:
- Screen Rationale : Increased resistance to virus
- Cell Type : Embryonic Fibroblast Cell Line [BTO:0001958]
- Cell Line : NIH 3T3 [BTO:0000944, CELLOSAURUS:CVCL_0594]
- Phenotype : Response To Virus
- Condition : Virus: CHIKV (Chikungunya virus) (1 MOI) [NCBI Taxid 371095]
- Library : GECKO v2 (mouse) [AddGene] | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : MaGeCK | Number of Hits: 1,118 | Full Dataset Size: 21,545
- Experimental Setup : Virus Exposure | Duration: 24 Hours | MOI: = 0.3
- Significance : Authors have indicated that results with Score.2 (p-Value) < 0.05 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Notes:
- Phenotypic readout: cell proliferation
- CHIKV is short for Chikungunya virus strain Senegal 37997
Score Distribution
< 1
> 0.0000000000000545