CRISPR Screen Dataset
Martin TD (2017) - 2-PMID28700943
Title: A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.
Screen Details:
- Screen Rationale : Cell-essential genes
- Cell Type : Colorectal Cancer Cell Line [BTO:0001616]
- Cell Line : HCT 116 [BTO:0001109, CELLOSAURUS:CVCL_0291]
- Phenotype : Cell Proliferation
- Library : CRISPRn (Martin, 2017) | Type: CRISPRn | Format: Pool | Enzyme: Cas9 | Methodology: Knockout
- Analysis Method : EdgeR | Number of Hits: 177 | Full Dataset Size: 18,158
- Experimental Setup : Timecourse | Duration: 10 Doublings | MOI: = 0.2
- Significance : Authors have indicated that results with Score.1 (Log2) < -2.0 AND Score.2 (q-Value) < 0.05 are to be considered significant. These results are indicated by '' in the HIT column of the table below.
Score Distribution
< 0.684171294
> -4.612121344