Related Resources

The Biological General Repository for Interaction Datasets (BioGRID) is an interaction, post-translational modification, and chemical association repository with data compiled through comprehensive curation efforts

CRISPR Screen data in BioGRID ORCS can be accessed via the BioGRID ORCS REST web service. Screens in various formats can be fetched from the BioGRID ORCS REST Service over HTTPS, programmatically or in a browser.

BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. Themed curation projects are updated monthly and additional projects are generated on a regular basis.


Latest News

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 82,024 publications. These additions bring our total number of non-redundant interactions to 2,035,517, raw interactions to 2,610,547, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: April 1st, 2023 - 01:41 PM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,882 publications. These additions bring our total number of non-redundant interactions to 2,030,323, raw interactions to 2,604,369, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: March 1st, 2023 - 04:10 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,725 publications. These additions bring our total number of non-redundant interactions to 2,020,444, raw interactions to 2,593,556, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: February 1st, 2023 - 04:16 PM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,599 publications. These additions bring our total number of non-redundant interactions to 2,009,467, raw interactions to 2,579,588, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: January 1st, 2023 - 07:08 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,370 publications. These additions bring our total number of non-redundant interactions to 2,002,486, raw interactions to 2,570,689, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: December 2nd, 2022 - 01:13 PM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,230 publications. These additions bring our total number of non-redundant interactions to 1,986,616, raw interactions to 2,551,504, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: November 1st, 2022 - 06:08 AM

The BioGRID ORCS curated CRISPR database has been updated to include CRISPR screens from a total of 282 different publications. These additions bring the total number of curated CRISPR screens in our database to 1,678 encompassing 93,000+ genes, 764 different cell lines, 129 different cell types, and 23 different phenotypes across 5 different organisms (Budding Yeast, Human, Mouse, African Green Monkey, and Fruit Fly). Additionally, we've curated 87 coronavirus-related screens including 52 specifically for SARS-CoV-2 (COVID-19).

New curated data are added to our CRISPR Database in curation updates on a regular basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these CRISPR data, visit our download page or utilize our web service.

Posted: May 4th, 2022 - 03:47 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 81,004 publications. These additions bring our total number of non-redundant interactions to 1,979,529, raw interactions to 2,541,478, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: October 1st, 2022 - 10:22 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 80,848 publications. These additions bring our total number of non-redundant interactions to 1,976,685, raw interactions to 2,537,592, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: September 1st, 2022 - 10:11 AM

Partners

National Institutes of Health
National Institutes of Health - Office of Research Infrastructure Programs
Canadian Institutes of Health Research
Lunenfeld-Tannenbaum Research Institute
Princeton University
Universite de Montreal

Latest Updates