Related Resources
The Biological General Repository for Interaction Datasets (BioGRID) is an interaction, post-translational modification, and chemical association repository with data compiled through comprehensive curation efforts
BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. Themed curation projects are updated monthly and additional projects are generated on a regular basis.
CRISPR Screen data in BioGRID ORCS can be accessed via the BioGRID ORCS REST web service. Screens in various formats can be fetched from the BioGRID ORCS REST Service over HTTPS, programmatically or in a browser.
Latest News
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 80,097 publications. These additions bring our total number of non-redundant interactions to 1,926,299, raw interactions to 2,475,167, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 79,845 publications. These additions bring our total number of non-redundant interactions to 1,920,021, raw interactions to 2,467,140, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID ORCS curated CRISPR database has been updated to include CRISPR screens from a total of 266 different publications. These additions bring the total number of curated CRISPR screens in our database to 1,592 encompassing 86,000+ genes, 745 different cell lines, 127 different cell types, and 23 different phenotypes across 4 different organisms (Human, Mouse, African Green Monkey, and Fruit Fly). Additionally, we've curated 53 coronavirus-related screens including 24 specifically for SARS-CoV-2 (COVID-19).
New curated data are added to our CRISPR Database in curation updates on a regular basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these CRISPR data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 79,570 publications. These additions bring our total number of non-redundant interactions to 1,890,467, raw interactions to 2,424,838, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 79,457 publications. These additions bring our total number of non-redundant interactions to 1,878,962, raw interactions to 2,412,071, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. All BioGRID Themed curation projects are updated monthly and the following is a listing of our current themed curation projects, and their statistics as of this update:
| Project | Proteins | Publications | Interactions | Chemical Interactions |
PTMs |
|---|---|---|---|---|---|
| COVID-19 Coronavirus | 110 | 507 | 28,576 | - | 156 |
| Ubiquitin-Proteasome System | 1,586 | 21,628 | 336,522 | 1,875 | 62,580 |
| Fanconi Anemia | 69 | 3,407 | 21,154 | 100 | 4,530 |
| Glioblastoma | 198 | 6,521 | 39,025 | 882 | 8,771 |
| Autophagy | 197 | 4,069 | 39,755 | 334 | 7,461 |
| Saccharomyces cerevisiae Kinome | 260 | 5,244 | 100,897 | - | 3,861 |
To view all BioGRID Themed Curation Projects, visit our project page. For more information on BioGRID curation of themed projects or if you're interested in contributing to a new or existing project, please contact us at biogridadmin@gmail.com.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 79,067 publications. These additions bring our total number of non-redundant interactions to 1,868,254, raw interactions to 2,398,355, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 78,774 publications. These additions bring our total number of non-redundant interactions to 1,864,111, raw interactions to 2,392,652, non-redundant chemical associations to 13,057, raw chemical associations to 29,417, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. All BioGRID Themed curation projects are updated monthly and the following is a listing of our current themed curation projects, and their statistics as of this update:
| Project | Proteins | Publications | Interactions | Chemical Interactions |
PTMs |
|---|---|---|---|---|---|
| COVID-19 Coronavirus | 110 | 473 | 28,423 | - | 156 |
| Ubiquitin-Proteasome System | 1,586 | 21,362 | 322,515 | 1,875 | 62,580 |
| Fanconi Anemia | 69 | 3,317 | 20,209 | 100 | 4,530 |
| Glioblastoma | 198 | 6,462 | 37,266 | 882 | 8,771 |
| Autophagy | 197 | 4,002 | 36,416 | 334 | 7,461 |
| Saccharomyces cerevisiae Kinome | 260 | 5,222 | 100,765 | - | 3,861 |
To view all BioGRID Themed Curation Projects, visit our project page. For more information on BioGRID curation of themed projects or if you're interested in contributing to a new or existing project, please contact us at biogridadmin@gmail.com.
