Areas of Interest

Create custom screen datasets based on search parameters. You can also download our entire dataset in a wide variety of standard formats.

Send us your datasets or link to BioGRID ORCS directly from your own website or database. Full details on how to contribute are available here.

We've developed tools that make use of BioGRID ORCS data. Check out the list of tools to see if we can help you work with our data.

Find out how many organisms, proteins, publications, and screens are available in the current release of the BioGRID ORCS.


Latest News

BioGRID update 3.5.167 includes a comprehensive update to our Arabidopsis thaliana dataset in partnership with The Bio-Analytic Resource for Plant Biology (BAR). This update incorporates an additional 13,000+ new interactions and helped to validate thousands of existing BioGRID interactions as well. Moreover, this increases the total number of Arabidopsis thaliana interactions deposited in BioGRID to 56,005 from 2,300+ publications. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find these and many additional plant biology resources available at bar.utoronto.ca.

A special thanks to the Bio-Analytic Resource (BAR) for their tireless curation efforts and in particular Eddi Esteban and Nick Provart (PI) for directly helping to facilitate the BioGRID collaboration.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

Posted: December 10th, 2018 - 06:33 PM

BioGRID update 3.5.167 includes a comprehensive update to our Drosophila melanogaster (Fruit Fly) dataset in ongoing partnership with FlyBase.org. This update verifies and validates more than 68,000 existing interactions and incorporates an additional 8,000+ new interactions across more than 6,100 total publications. This update also increases the total number of Drosophila melanogaster interactions deposited in BioGRID to 76,657. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find them available at FlyBase.org in all search result pages.

A special thanks to the entire FlyBase Consortium for their tireless curation efforts and in particular Julie Agapite and Gil dos Santos for directly helping to facilitate the BioGRID collaboration.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

Posted: December 1st, 2018 - 01:43 PM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,763 publications. These additions bring our total number of non-redundant interactions to 1,279,126, raw interactions to 1,650,607, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: December 1st, 2018 - 03:13 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,477 publications. These additions bring our total number of non-redundant interactions to 1,255,578, raw interactions to 1,623,645, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: November 1st, 2018 - 05:12 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 66,164 publications. These additions bring our total number of non-redundant interactions to 1,243,659, raw interactions to 1,607,037, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: September 26th, 2018 - 09:41 AM

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,816 publications. These additions bring our total number of non-redundant interactions to 1,238,062, raw interactions to 1,598,688, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: September 1st, 2018 - 03:22 AM

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,518 publications. These additions bring our total number of non-redundant interactions to 1,232,786, raw interactions to 1,591,402, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: August 1st, 2018 - 02:05 AM

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,386 publications. These additions bring our total number of non-redundant interactions to 1,230,943, raw interactions to 1,588,606, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: July 1st, 2018 - 06:18 AM

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,218 publications. These additions bring our total number of non-redundant interactions to 1,228,924, raw interactions to 1,585,828, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: June 1st, 2018 - 03:18 AM

Latest Updates