Related Projects

The Biological General Repository for Interaction Datasets (BioGRID) is an interaction, post-translational modification, and chemical association repository with data compiled through comprehensive curation efforts

This BioGRID project page is designed to allow exploration of the entire yeast kinome and its interactions, including genetic interactions and all mapped sites of protein phosphorylation.

CRISPR Screen data in BioGRID ORCS can be accessed via the BioGRID ORCS REST web service. Screens in various formats can be fetched from the BioGRID ORCS REST Service over HTTPS, programmatically or in a browser.


Latest News

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 68,754 publications. These additions bring our total number of non-redundant interactions to 1,294,082, raw interactions to 1,670,339, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: March 1st, 2019 - 03:03 AM

Gene Info is an open source extension for the Chrome web browser that allows automated retrieval of gene annotation information for any gene name, synonym or supported accession number on an open web page within Chrome. Searching or double-clicking on text terms retrieves gene function annotation, GO terms, external database links, and interaction data drawn from BioGRID and IntAct. Retrieved gene names are automatically hyperlinked for rapid recursive searches.

GeneInfo is fully open source, available online at GitHub and is downloadable here. Tutorial videos and a step-by-step guide is available online. GeneInfo was developed by James Knight in the Gingras Lab at the Lunenfeld-Tanenbaum Research Institute in Toronto, Canada.

Posted: February 25th, 2019 - 08:52 PM

The BioGRID ORCS curated set of data have been updated to include CRISPR screens from a total of 43 different publications. These additions bring our total number of curated CRISPR screens to 561 encompassing 58,000+ genes, 431 different cell lines, and 113 different cell types across 3 different model organisms species (Human, Mouse, and Fruit Fly).

New curated data are added in curation updates on a regular basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these CRISPR data, visit our download page or utilize our web service.

Posted: February 22nd, 2019 - 07:23 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 68,514 publications. These additions bring our total number of non-redundant interactions to 1,288,948, raw interactions to 1,664,026, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: February 1st, 2019 - 07:23 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 68,215 publications. These additions bring our total number of non-redundant interactions to 1,285,194, raw interactions to 1,658,808, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: January 1st, 2019 - 02:29 AM

BioGRID update 3.5.167 includes a comprehensive update to our Arabidopsis thaliana dataset in partnership with The Bio-Analytic Resource for Plant Biology (BAR). This update incorporates an additional 13,000+ new interactions and helped to validate thousands of existing BioGRID interactions as well. Moreover, this increases the total number of Arabidopsis thaliana interactions deposited in BioGRID to 56,005 from 2,300+ publications. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find these and many additional plant biology resources available at bar.utoronto.ca.

A special thanks to the Bio-Analytic Resource (BAR) for their tireless curation efforts and in particular Eddi Esteban and Nick Provart (PI) for directly helping to facilitate the BioGRID collaboration.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

Posted: December 10th, 2018 - 06:33 PM

BioGRID update 3.5.167 includes a comprehensive update to our Drosophila melanogaster (Fruit Fly) dataset in ongoing partnership with FlyBase.org. This update verifies and validates more than 68,000 existing interactions and incorporates an additional 8,000+ new interactions across more than 6,100 total publications. This update also increases the total number of Drosophila melanogaster interactions deposited in BioGRID to 76,657. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find them available at FlyBase.org in all search result pages.

A special thanks to the entire FlyBase Consortium for their tireless curation efforts and in particular Julie Agapite and Gil dos Santos for directly helping to facilitate the BioGRID collaboration.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

Posted: December 1st, 2018 - 01:43 PM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,763 publications. These additions bring our total number of non-redundant interactions to 1,279,126, raw interactions to 1,650,607, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: December 1st, 2018 - 03:13 AM

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,477 publications. These additions bring our total number of non-redundant interactions to 1,255,578, raw interactions to 1,623,645, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

Posted: November 1st, 2018 - 05:12 AM

Partners

National Institutes of Health
National Institutes of Health - Office of Research Infrastructure Programs
Canadian Institutes of Health Research
Lunenfeld-Tannenbaum Research Institute
Princeton University
Universite de Montreal

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